Managing and querying gene expression data using Curray.

Managing and querying gene expression data using Curray.

BACKGROUND
In principle, the gene expression data can be seen as providing only a three-valued expression profile relative biological element target experiment at hand. Although complicated, collect expression profile does not pose much of a challenge from the standpoint of the query language. What is interesting is how the expression profiles are used to tease out information from a vast array of repository information that ascribe meaning to the expression profile.

Because of the inherent experimenting explanation of certain functions, much the same way as the query in the database, developing a query system for gene expression data seems futile. Instead, develop tools and techniques to support the individual tasks have been considered prudent in contemporary research.


RESULTS
We propose gene expression data management and query system that is capable of supporting the pre-expression, expression and analysis of post-expression levels and reducing the impedance mismatch between the system analysis. To this end, we propose a new, platform-independent and general purpose query language called curray, for a query language Custom microarrays, to support the online data expression analysis using distributed resources.

It includes features for designing pipelines using expression analysis at the conceptual level language constructs. The ability to include user function defined as a class language feature facilitates the support limited analysis and eliminates the limitations of language. We show that this curray declarative and extensible agile feature enables the modeling of flexible and space for customization.


CONCLUSION
The development proposed in this article allows the user to see their expression data from a conceptual standpoint – experiment, probe, expression, mapping, etc. at various levels of representation and is independent of the underlying chip technology. It also allows transparent roll-up and drill-down along a hierarchical representation of the raw data to standard as MIAME and MAGE-ML uses linguistic construction. Curray also allows integration with distributed web resources through its LifeDB system which is a part.

 Managing and querying gene expression data using Curray.
Managing and querying gene expression data using Curray.

EMERALD contribution of the project to assess and improve the quality of microarray data.

While the minimum information about the trial microarray (MIAME) standards have helped to increase the value of microarray data deposited into the general database as ArrayExpress and Gene Expression Omnibus (GEO), limited means have been provided to assess the quality of this data or to identify the procedures used to normalize and transforms raw data.

The EMERALD FP6 Coordination Action is designed to provide an approach to assess and improve the overall quality of microarray data and to disseminate to the public microarray approach through a comprehensive series of workshops, tutorials, and symposia. Tools developed to assess the quality of data used to demonstrate how low-quality data deletion can increase the power of statistical analysis and facilitate the analysis of multiple microarray data sets together.

N3-PEG-BIOTIN,500

33-HE006041-500
  • EUR 992.40
  • EUR 2856.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Biotin-PEG-COOH,500

33-HE041017-500
  • EUR 726.00
  • EUR 2056.80
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SH-PEG-SH,500

33-HO003003-500
  • EUR 310.80
  • EUR 812.40
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

AlKyne-PEG-AlKyne,500

33-HO007007-500
  • EUR 339.60
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  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

COOH-PEG-COOH,500

33-HO017017-500
  • EUR 200.40
  • EUR 478.80
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SC-PEG-SC,500

33-HO023023-500
  • EUR 200.40
  • EUR 478.80
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SH-PEG-NH2,500

33-HE003005-500
  • EUR 1909.20
  • EUR 681.60
  • 5g
  • g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

MAL-PEG-NH2,500

33-HE022005-500
  • EUR 622.80
  • EUR 1747.20
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

NH2-PEG-NH2,500

33-HO005005-500
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  • EUR 726.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

N3-PEG-N3,500

33-HO006006-500
  • EUR 367.20
  • EUR 979.20
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

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ERLENMEYER FLASK, 500 ML, PP

4985P-500 6/pk
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REAGENT BOTTLE,500 ML, PP

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M02416-3 100uL
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DBCO-PEG-Biotin,500

HE048041-500-100mg 100mg
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JBS Solubility Kit HTS

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JBScreen Thermofluor FUNDAMENT HTS

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Human Apolipoprotein B (Apo B) AssayMax ELISA Kit (Positive Control included)

EA7001-7 96 Well Plate
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Human Apolipoprotein E (Apo E) AssayMax ELISA Kit (Positive Control included)

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Recombinant Human Galectin-7

7-00442 2µg Ask for price

Recombinant Human Galectin-7

7-00443 10µg Ask for price

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Recombinant Transmembrane Protease Serine 2 Protein, Partial

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Recombinant TMPRSS2 Protein, Partial

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Recombinant Novel Coronavirus Spike Glycoprotein(S), Partial

E80018
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  • 20 ul
  • 100 ul
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Turbidity Std Ratio 500 NTU

CRSR-500-100 100ML
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Dreschel Head Mf48/03/500

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Human Apolipoprotein A-I (Apo A1) AssayMax ELISA Kit (Positive Control included)

EA5201-7 96 Well Plate
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Human Apolipoprotein A-II (Apo A2) AssayMax ELISA Kit (Positive Control included)

EA5222-7 96 Well Plate
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Human Apolipoprotein A-I (Apo A1) AssayMax ELISA Kit (Positive Control included)

EA5301-7 96 Well Plate
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Human Apolipoprotein H (Apo H, B2GP1) AssayMax ELISA Kit (Positive Control included)

EA8821-7 96 Well Plate
EUR 572.4

Human Bone Morphogenic Protein 7 (BMP-7) ELISA Kit, 96 tests, Quantitative

100-190-B7H 1 Kit
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Genorise® Plasmid DNA Extraction Kit 500

GR101073-500 500
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Genorise® Universal DNA Mini Kit 500

GR101077-500 500
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Genorise® Bone DNA Extraction Kit-500

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Genorise® Soil DNA Extraction Kit-500

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Genorise® Stool DNA Extraction Kit-500

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Human thymidylate kinase (TMK) - for 500 assays

HTMK-500 500 assays
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Human Airway FibrOut1: Fibroblast Inhibitory System (for 500 ml medium)

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Human Airway FibrOut2: Fibroblast Inhibitory System (for 500 ml medium)

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Human Airway FibrOut3: Fibroblast Inhibitory System (for 500 ml medium)

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Human Aorta FibrOut: Fibroblast Inhibitory System (for 500 ml medium)

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Human Artery FibrOut: Fibroblast Inhibitory System (for 500 ml medium)

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Human Bladder FibrOut3: Fibroblast Inhibitory System (for 500 ml medium)

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Human Bone FibrOut: Fibroblast Inhibitory System (for 500 ml medium)

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Human Brain FibrOut2: Fibroblast Inhibitory System (for 500 ml medium)

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Human Brain FibrOut3: Fibroblast Inhibitory System (for 500 ml medium)

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Human Brain FibrOut4: Fibroblast Inhibitory System (for 500 ml medium)

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Human Brain FibrOut5: Fibroblast Inhibitory System (for 500 ml medium)

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Human Brain FibrOut6: Fibroblast Inhibitory System (for 500 ml medium)

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Human Brain FibrOut7: Fibroblast Inhibitory System (for 500 ml medium)

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Human Brain FibrOut8: Fibroblast Inhibitory System (for 500 ml medium)

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Human Brain FibrOut9: Fibroblast Inhibitory System (for 500 ml medium)

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Human Brain FibrOut10: Fibroblast Inhibitory System (for 500 ml medium)

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Human Breast FibrOut: Fibroblast Inhibitory System (for 500 ml medium)

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Human Cartilage FibrOut: Fibroblast Inhibitory System (for 500 ml medium)

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Human Cervix FibrOut1: Fibroblast Inhibitory System (for 500 ml medium)

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Human Embryo FibrOut1: Fibroblast Inhibitory System (for 500 ml medium)

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Human Embryo FibrOut3: Fibroblast Inhibitory System (for 500 ml medium)

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Human Embryo FibrOut4: Fibroblast Inhibitory System (for 500 ml medium)

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Human Endothelium FibrOut: Fibroblast Inhibitory System (for 500 ml medium)

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Human Esophagus FibrOut1: Fibroblast Inhibitory System (for 500 ml medium)

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Human Eye FibrOut4: Fibroblast Inhibitory System (for 500 ml medium)

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Human Fat FibrOut1: Fibroblast Inhibitory System (for 500 ml medium)

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Human Fat FibrOut3: Fibroblast Inhibitory System (for 500 ml medium)

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The tool quality metrics have been disseminated through publications and through arrayQualityMetrics software package. Within the framework provided by the Ontology for Biomedical Investigations, ontology developed to describe the transformation of the data, and software ontology developed for gene expression analysis software. In addition, the consortium has advocated for the development and use of an external reference standard in microarray hybridization and create Molecular Methods (MolMeth) database, which provides the main source for the methods and protocols focusing on microarray-based technology.

Trevor

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