Integrated metabolite and gene expression profiles identify lipid biomarkers associated with progression of hepatocellular carcinoma and patient outcomes.
OBJECTIVE
We combined gene expression and metabolic profile analysis to identify factors associated with the outcomes of patients with hepatocellular carcinoma (HCC).
METHOD
We compared the pattern of metabolism and gene expression between paired tumor and nontumor tissue from 30 patients with HCC, and validated the results using a sample of 356 patients with HCC. A total of 469 metabolites were measured by using chromatography / mass spectrometry spectrometry liquid and gas chromatography / mass. Metabolism and integrated genomic data, and Kaplan-Meier and Cox proportional hazards analysis was used to a certain pattern associate with patient outcomes. related factors were evaluated for their effect on cancer cells in vitro and tumor formation in nude mice.
RESULTS
We identified 28 metabolites and 169 genes associated with aggressive HCC. lipid metabolite-stearoyl-CoA desaturase (SCD) is associated with the aberrant activity of palmitate signal in aggressive HCC samples. The expression of gene products associated with these metabolites, including SCD, was independently associated with survival time and recurrence of tumors in test and validation sets.
The combined expression of SCD and α-fetoprotein associated with outcomes of patients with early-stage liver cancer. Levels of monounsaturated palmitic acid, the product of SCD activity, an increase in aggressive HCCS; monounsaturated palmitic acid increased migration and invasion of HCC cells cultured and colony formation by liver cancer cells. HCC cells expressed small interfering RNA against SCD decreased cell migration and the formation of colonies in culture and reduced tumorigenicity in mice.
CONCLUSION
By using a combination of gene expression and metabolic profile analysis, we identified a network of lipogenic involving SCD and palmitic signal and associated with the development of HCC and patient outcomes. Microarray platform and data that has been submitted to the Gene Expression Omnibus at NCBI public database following the guidelines MIAME. accession numbers: GPL4700 (platform), and GSE6857 (sample).
Interferome v2.0: updated database of interferon-regulated genes described.
Interferome v2.0 is an update of an earlier version of DB Interferome NAR published in the 2009 edition of the database. Much better computing infrastructure now allows more complex and faster queries, and supports more data sets of types I, II and III interferon (IFN) -treated cells, rat or human.
Quantitative, MIAME appropriate data is collected, carried out a thorough analysis, standardized, quantitative and statistical and then significant changes in gene expression are uploaded. a comprehensive manual collection of metadata in v2.0 allows flexible, detailed searches capacity including the parameters: range double change, the type of IFN, concentration and time, and cell / tissue types.
JBScreen Classic 2 |
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CS-102L | Jena Bioscience GmbH | 24solutions | EUR 217.8 |
JBScreen Classic 3 |
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CS-103L | Jena Bioscience GmbH | 24solutions | EUR 217.8 |
JBScreen Classic 4 |
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CS-104L | Jena Bioscience GmbH | 24solutions | EUR 217.8 |
JBScreen Classic 5 |
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CS-105L | Jena Bioscience GmbH | 24solutions | EUR 217.8 |
JBScreen Classic 6 |
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CS-106L | Jena Bioscience GmbH | 24solutions | EUR 217.8 |
JBScreen Classic 7 |
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CS-107L | Jena Bioscience GmbH | 24solutions | EUR 217.8 |
JBScreen Classic 8 |
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CS-108L | Jena Bioscience GmbH | 24solutions | EUR 217.8 |
JBScreen Classic 9 |
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CS-109L | Jena Bioscience GmbH | 24solutions | EUR 217.8 |
JBScreen Classic 10 |
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CS-110L | Jena Bioscience GmbH | 24solutions | EUR 217.8 |
JBScreen Classic 1 - 5 |
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CS-112L | Jena Bioscience GmbH | 5Kits | EUR 870 |
JBScreen Classic 6 - 10 |
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CS-113L | Jena Bioscience GmbH | 5Kits | EUR 870 |
JBScreen Classic 1 - 10 |
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CS-114L | Jena Bioscience GmbH | 10Kits | EUR 1611.8 |
JBScreen Classic 1 - 5 |
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M-CS-112L | MiTeGen | 5 Kits | EUR 1082 |
Description: JBScreen Classic 1 - 5 |
JBScreen Classic 6 - 10 |
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M-CS-113L | MiTeGen | 5 Kits | EUR 1082 |
Description: JBScreen Classic 6 - 10 |
JBScreen Classic 1 - 10 |
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M-CS-114L | MiTeGen | 10 Kits | EUR 2005 |
Description: JBScreen Classic 1 - 10 |
JBScreen Classic 7 (MPD based) |
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M-CS-107L | MiTeGen | 24 solutions | EUR 249 |
Description: JBScreen Classic 7 (MPD based) |
JBScreen Classic 10 (Salt based) |
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M-CS-110L | MiTeGen | 24 solutions | EUR 249 |
Description: JBScreen Classic 10 (Salt based) |
JBScreen Classic HTS II L (1.7 ml per well) (Ammonium Sulfate, MPD, Alcohol and Salt based) |
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M-CS-202L | MiTeGen | 96 solutions | EUR 377 |
Description: JBScreen Classic HTS II L (1.7 ml per well) (Ammonium Sulfate, MPD, Alcohol and Salt based) |
JBScreen Classic 2 (PEG 4000 based) |
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M-CS-102L | MiTeGen | 24 solutions | EUR 249 |
Description: JBScreen Classic 2 (PEG 4000 based) |
JBScreen Classic 3 (PEG 4000+ based) |
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M-CS-103L | MiTeGen | 24 solutions | EUR 249 |
Description: JBScreen Classic 3 (PEG 4000+ based) |
JBScreen Classic 8 (MPD/Alcohol based) |
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M-CS-108L | MiTeGen | 24 solutions | EUR 249 |
Description: JBScreen Classic 8 (MPD/Alcohol based) |
JBScreen Classic 9 (Alcohol/Salt based) |
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M-CS-109L | MiTeGen | 24 solutions | EUR 249 |
Description: JBScreen Classic 9 (Alcohol/Salt based) |
JBScreen Classic 6 (Ammonium Sulfate based) |
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M-CS-106L | MiTeGen | 24 solutions | EUR 249 |
Description: JBScreen Classic 6 (Ammonium Sulfate based) |
JBScreen Classic 1 (PEG 400 to 3000 based) |
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M-CS-101L | MiTeGen | 24 solutions | EUR 249 |
Description: JBScreen Classic 1 (PEG 400 to 3000 based) |
JBScreen Classic 5 (PEG 8000 to 20000 based) |
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M-CS-105L | MiTeGen | 24 solutions | EUR 249 |
Description: JBScreen Classic 5 (PEG 8000 to 20000 based) |
JBScreen Classic 4 (PEG 5000 MME to 8000 based) |
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M-CS-104L | MiTeGen | 24 solutions | EUR 249 |
Description: JBScreen Classic 4 (PEG 5000 MME to 8000 based) |
JBScreen LCP HTS |
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CS-213L | Jena Bioscience GmbH | 96solutions | EUR 467.6 |
JBScreen LCP HTS |
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M-CS-213L | MiTeGen | 96 solutions | EUR 535 |
Description: JBScreen LCP HTS |
JBScreen JCSG++ HTS |
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CS-206L | Jena Bioscience GmbH | 96solutions | EUR 345 |
JBScreen PACT++ HTS |
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CS-207L | Jena Bioscience GmbH | 96solutions | EUR 345 |
JBScreen Plus HTS |
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CS-507L | Jena Bioscience GmbH | 96solutions | EUR 771.6 |
JBScreen Basic HTS |
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CS-203L | Jena Bioscience GmbH | 96solutions | EUR 329.4 |
JBScreen Kinase HTS |
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CS-204L | Jena Bioscience GmbH | 96solutions | EUR 542.8 |
JBScreen Detergents HTS |
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M-CS-525 | MiTeGen | 96 solutions | EUR 789 |
Description: JBScreen Detergents HTS |
JBScreen Pentaerythritol HTS |
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CS-210L | Jena Bioscience GmbH | 96solutions | EUR 542.8 |
JBScreen PEG/Salt HTS |
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CS-205L | Jena Bioscience GmbH | 96solutions | EUR 345 |
JBScreen Nuc-Pro HTS |
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CS-209L | Jena Bioscience GmbH | 96solutions | EUR 543 |
JBScreen Wizard 1 & 2 HTS |
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CS-318 | Jena Bioscience GmbH | 96solutions | EUR 329.4 |
JBScreen Thermofluor SPECIFIC HTS |
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M-CS-333 | MiTeGen | 93 solutions | EUR 397 |
Description: JBScreen Thermofluor SPECIFIC HTS |
JBScreen Thermofluor FUNDAMENT HTS |
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M-CS-332 | MiTeGen | 93 solutions | EUR 397 |
Description: JBScreen Thermofluor FUNDAMENT HTS |
JBScreen Membrane 1 - 4 & JBScreen Detergents HTS (4 + 1 Kits) |
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M-CS-308 | MiTeGen | 4 + 1 Kits | EUR 2129 |
Description: JBScreen Membrane 1 - 4 & JBScreen Detergents HTS (4 + 1 Kits) |
JBScreen Membrane HTS (1.7ml per well) |
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M-CS-310 | MiTeGen | 96 solutions | EUR 621 |
Description: JBScreen Membrane HTS (1.7ml per well) |
JBScreen JCSG++ HTS L (1.7 ml per well) |
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M-CS-206L | MiTeGen | 96 solutions | EUR 395 |
Description: JBScreen JCSG++ HTS L (1.7 ml per well) |
JBScreen PACT++ HTS L (1.7 ml per well) |
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M-CS-207L | MiTeGen | 96 solutions | EUR 395 |
Description: JBScreen PACT++ HTS L (1.7 ml per well) |
JBScreen Plus HTS L (1.0 ml per well) |
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M-CS-507L | MiTeGen | 96 solutions | EUR 883 |
Description: JBScreen Plus HTS L (1.0 ml per well) |
JBScreen Basic HTS L (1.7 ml per well) |
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M-CS-203L | MiTeGen | 96 solutions | EUR 377 |
Description: JBScreen Basic HTS L (1.7 ml per well) |
JBScreen Kinase HTS L (1.7 ml per well) |
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M-CS-204L | MiTeGen | 96 solutions | EUR 621 |
Description: JBScreen Kinase HTS L (1.7 ml per well) |
JBScreen PEG/Salt HTS L (1.7 ml per well) |
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M-CS-205L | MiTeGen | 96 solutions | EUR 395 |
Description: JBScreen PEG/Salt HTS L (1.7 ml per well) |
JBScreen Nuc-Pro HTS L (1.7 ml per well) |
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M-CS-209L | MiTeGen | 96 solutions | EUR 508 |
Description: JBScreen Nuc-Pro HTS L (1.7 ml per well) |
JBScreen Pentaerythritol HTS L (1.7 ml per well) |
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M-CS-210L | MiTeGen | 96 solutions | EUR 621 |
Description: JBScreen Pentaerythritol HTS L (1.7 ml per well) |
JBScreen LCP |
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CS-340 | Jena Bioscience GmbH | 4 x 24solutions | EUR 936.3 |
JBScreen LCP |
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M-CS-340 | MiTeGen | 4 x 24 solutions | EUR 1165 |
Description: JBScreen LCP |
JBScreen Buffers |
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CS-214 | Jena Bioscience GmbH | 84solutions | EUR 345 |
JBScreen Buffers |
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M-CS-214 | MiTeGen | 84 solutions | EUR 395 |
Description: JBScreen Buffers |
JBScreen JCSG++ 1 |
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CS-151 | Jena Bioscience GmbH | 24solutions | EUR 229.9 |
JBScreen JCSG++ 2 |
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CS-152 | Jena Bioscience GmbH | 24solutions | EUR 229.9 |
JBScreen JCSG++ 3 |
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CS-153 | Jena Bioscience GmbH | 24solutions | EUR 229.9 |
JBScreen JCSG++ 4 |
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CS-154 | Jena Bioscience GmbH | 24solutions | EUR 229.9 |
JBScreen PACT++ 1 |
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CS-161 | Jena Bioscience GmbH | 24solutions | EUR 229.9 |
JBScreen PACT++ 2 |
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CS-162 | Jena Bioscience GmbH | 24solutions | EUR 229.9 |
JBScreen PACT++ 3 |
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CS-163 | Jena Bioscience GmbH | 24solutions | EUR 229.9 |
JBScreen PACT++ 4 |
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CS-164 | Jena Bioscience GmbH | 24solutions | EUR 229.9 |
JBScreen JCSG++ 1 |
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M-CS-151 | MiTeGen | 24 solutions | EUR 263 |
Description: JBScreen JCSG++ 1 |
JBScreen JCSG++ 2 |
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M-CS-152 | MiTeGen | 24 solutions | EUR 263 |
Description: JBScreen JCSG++ 2 |
JBScreen JCSG++ 3 |
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M-CS-153 | MiTeGen | 24 solutions | EUR 263 |
Description: JBScreen JCSG++ 3 |
JBScreen JCSG++ 4 |
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M-CS-154 | MiTeGen | 24 solutions | EUR 263 |
Description: JBScreen JCSG++ 4 |
JBScreen PACT++ 1 |
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M-CS-161 | MiTeGen | 24 solutions | EUR 263 |
Description: JBScreen PACT++ 1 |
JBScreen PACT++ 2 |
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M-CS-162 | MiTeGen | 24 solutions | EUR 263 |
Description: JBScreen PACT++ 2 |
JBScreen PACT++ 3 |
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M-CS-163 | MiTeGen | 24 solutions | EUR 263 |
Description: JBScreen PACT++ 3 |
JBScreen PACT++ 4 |
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M-CS-164 | MiTeGen | 24 solutions | EUR 263 |
Description: JBScreen PACT++ 4 |
JBScreen Basic 1 |
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CS-121 | Jena Bioscience GmbH | 24solutions | EUR 217.8 |
JBScreen Basic 2 |
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CS-122 | Jena Bioscience GmbH | 24solutions | EUR 217.8 |
JBScreen Basic 3 |
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CS-123 | Jena Bioscience GmbH | 24solutions | EUR 217.8 |
JBScreen Basic 4 |
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CS-124 | Jena Bioscience GmbH | 24solutions | EUR 217.8 |
JBScreen Basic 1 |
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M-CS-121 | MiTeGen | 24 solutions | EUR 249 |
Description: JBScreen Basic 1 |
JBScreen Basic 2 |
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M-CS-122 | MiTeGen | 24 solutions | EUR 249 |
Description: JBScreen Basic 2 |
JBScreen Basic 3 |
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M-CS-123 | MiTeGen | 24 solutions | EUR 249 |
Description: JBScreen Basic 3 |
JBScreen Basic 4 |
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M-CS-124 | MiTeGen | 24 solutions | EUR 249 |
Description: JBScreen Basic 4 |
JBScreen Kinase 1 |
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CS-131 | Jena Bioscience GmbH | 24solutions | EUR 361.5 |
JBScreen Kinase 2 |
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CS-132 | Jena Bioscience GmbH | 24solutions | EUR 361.5 |
JBScreen Kinase 3 |
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CS-133 | Jena Bioscience GmbH | 24solutions | EUR 361.5 |
JBScreen Kinase 4 |
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CS-134 | Jena Bioscience GmbH | 24solutions | EUR 361.5 |
JBScreen Wizard 1 |
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CS-311 | Jena Bioscience GmbH | 48solutions | EUR 435.6 |
JBScreen Wizard 2 |
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CS-312 | Jena Bioscience GmbH | 48solutions | EUR 435.6 |
JBScreen Kinase 1 |
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M-CS-131 | MiTeGen | 24 solutions | EUR 414 |
Description: JBScreen Kinase 1 |
JBScreen Kinase 2 |
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M-CS-132 | MiTeGen | 24 solutions | EUR 414 |
Description: JBScreen Kinase 2 |
JBScreen Kinase 3 |
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M-CS-133 | MiTeGen | 24 solutions | EUR 414 |
Description: JBScreen Kinase 3 |
JBScreen Kinase 4 |
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M-CS-134 | MiTeGen | 24 solutions | EUR 414 |
Description: JBScreen Kinase 4 |
JBScreen Plus Salts |
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CS-503 | Jena Bioscience GmbH | 24solutions | EUR 241 |
JBScreen Plus Salts |
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M-CS-503 | MiTeGen | 24 solutions | EUR 276 |
Description: JBScreen Plus Salts |
JBScreen Membrane 1 |
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CS-301L | Jena Bioscience GmbH | 24solutions | EUR 361.5 |
JBScreen Membrane 2 |
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CS-302L | Jena Bioscience GmbH | 24solutions | EUR 361.5 |
JBScreen Membrane 3 |
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CS-303L | Jena Bioscience GmbH | 24solutions | EUR 361.5 |
JBScreen Membrane 4 |
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CS-304L | Jena Bioscience GmbH | 24solutions | EUR 361.5 |
JBScreen Plus Complete all 5 JBScreen Plus kits for a special price |
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M-CS-506 | MiTeGen | 5 Kits | EUR 1103 |
Description: JBScreen Plus Complete all 5 JBScreen Plus kits for a special price |
JBScreen Plus Complete |
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CS-506 | Jena Bioscience GmbH | 5Kits | EUR 963.9 |
JBScreen Detergents 1 |
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M-CS-521 | MiTeGen | 24 solutions | EUR 263 |
Description: JBScreen Detergents 1 |
JBScreen Detergents 2 |
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M-CS-522 | MiTeGen | 24 solutions | EUR 263 |
Description: JBScreen Detergents 2 |
JBScreen Detergents 3 |
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M-CS-523 | MiTeGen | 24 solutions | EUR 263 |
Description: JBScreen Detergents 3 |
JBScreen Detergents 4 |
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M-CS-524 | MiTeGen | 24 solutions | EUR 263 |
Description: JBScreen Detergents 4 |
JBScreen JCSG++ 1 - 4 |
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CS-155 | Jena Bioscience GmbH | 4Kits | EUR 689.8 |
JBScreen PACT++ 1 - 4 |
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CS-165 | Jena Bioscience GmbH | 4Kits | EUR 689.8 |
JBScreen JCSG++ 1 - 4 |
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M-CS-155 | MiTeGen | 4 Kits | EUR 858 |
Description: JBScreen JCSG++ 1 - 4 |
JBScreen PACT++ 1 - 4 |
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M-CS-165 | MiTeGen | 4 Kits | EUR 858 |
Description: JBScreen PACT++ 1 - 4 |
JBScreen Buffers Xtreme |
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CS-215 | Jena Bioscience GmbH | 84solutions | EUR 345 |
JBScreen Plus Additives |
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CS-504 | Jena Bioscience GmbH | 24solutions | EUR 241 |
JBScreen Plus Volatiles |
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CS-505 | Jena Bioscience GmbH | 24solutions | EUR 241 |
JBScreen Buffers Xtreme |
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M-CS-215 | MiTeGen | 84 solutions | EUR 395 |
Description: JBScreen Buffers Xtreme |
JBScreen Plus Additives |
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M-CS-504 | MiTeGen | 24 solutions | EUR 276 |
Description: JBScreen Plus Additives |
JBScreen Plus Volatiles |
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M-CS-505 | MiTeGen | 24 solutions | EUR 276 |
Description: JBScreen Plus Volatiles |
JBScreen Basic 1 - 4 |
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CS-125 | Jena Bioscience GmbH | 4Kits | EUR 653.4 |
JBScreen PEG/Salt 1 |
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CS-141 | Jena Bioscience GmbH | 24solutions | EUR 229.9 |
JBScreen PEG/Salt 2 |
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CS-142 | Jena Bioscience GmbH | 24solutions | EUR 229.9 |
JBScreen PEG/Salt 3 |
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CS-143 | Jena Bioscience GmbH | 24solutions | EUR 229.9 |
JBScreen PEG/Salt 4 |
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CS-144 | Jena Bioscience GmbH | 24solutions | EUR 229.9 |
JBScreen Basic 1 - 4 |
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M-CS-125 | MiTeGen | 4 Kits | EUR 813 |
Description: JBScreen Basic 1 - 4 |
JBScreen PEG/Salt 1 |
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M-CS-141 | MiTeGen | 24 solutions | EUR 263 |
Description: JBScreen PEG/Salt 1 |
JBScreen PEG/Salt 2 |
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M-CS-142 | MiTeGen | 24 solutions | EUR 263 |
Description: JBScreen PEG/Salt 2 |
JBScreen PEG/Salt 3 |
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M-CS-143 | MiTeGen | 24 solutions | EUR 263 |
Description: JBScreen PEG/Salt 3 |
JBScreen PEG/Salt 4 |
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M-CS-144 | MiTeGen | 24 solutions | EUR 263 |
Description: JBScreen PEG/Salt 4 |
JBScreen Plus Chaotropic |
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M-CS-502 | MiTeGen | 24 solutions | EUR 276 |
Description: JBScreen Plus Chaotropic |
JBScreen Kinase 1 - 4 |
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CS-135 | Jena Bioscience GmbH | 4Kits | EUR 1084.5 |
JBScreen Nuc-Pro 1 |
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CS-181 | Jena Bioscience GmbH | 24solutions | EUR 362 |
JBScreen Nuc-Pro 2 |
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CS-182 | Jena Bioscience GmbH | 24solutions | EUR 362 |
JBScreen Nuc-Pro 3 |
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CS-183 | Jena Bioscience GmbH | 24solutions | EUR 362 |
JBScreen Nuc-Pro 4 |
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CS-184 | Jena Bioscience GmbH | 24solutions | EUR 362 |
JBScreen Wizard 1 & 2 |
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CS-315 | Jena Bioscience GmbH | 2Kits | EUR 826.9 |
JBScreen Kinase 1 - 4 |
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M-CS-135 | MiTeGen | 4 Kits | EUR 1349 |
Description: JBScreen Kinase 1 - 4 |
JBScreen Nuc-Pro 1 |
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M-CS-181 | MiTeGen | 24 solutions | EUR 414 |
Description: JBScreen Nuc-Pro 1 |
JBScreen Nuc-Pro 2 |
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M-CS-182 | MiTeGen | 24 solutions | EUR 414 |
Description: JBScreen Nuc-Pro 2 |
JBScreen Nuc-Pro 3 |
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M-CS-183 | MiTeGen | 24 solutions | EUR 414 |
Description: JBScreen Nuc-Pro 3 |
JBScreen Nuc-Pro 4 |
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M-CS-184 | MiTeGen | 24 solutions | EUR 414 |
Description: JBScreen Nuc-Pro 4 |
JBScreen Plus Kosmotropic |
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CS-501 | Jena Bioscience GmbH | 24solutions | EUR 241 |
JBScreen Plus Kosmotropic |
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M-CS-501 | MiTeGen | 24 solutions | EUR 276 |
Description: JBScreen Plus Kosmotropic |
JBScreen Membrane 1 - 4 |
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CS-309 | Jena Bioscience GmbH | 4Kits | EUR 1084.5 |
JBScreen Pentaerythritol 1 |
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CS-191 | Jena Bioscience GmbH | 24solutions | EUR 361.5 |
JBScreen Pentaerythritol 2 |
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CS-192 | Jena Bioscience GmbH | 24solutions | EUR 361.5 |
JBScreen Pentaerythritol 3 |
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CS-193 | Jena Bioscience GmbH | 24solutions | EUR 361.5 |
JBScreen Pentaerythritol 4 |
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CS-194 | Jena Bioscience GmbH | 24solutions | EUR 361.5 |
JBScreen Thermofluor SPECIFIC |
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CS-333 | Jena Bioscience GmbH | 93solutions | EUR 347.1 |
JBScreen PEG/Salt 1 - 4 |
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CS-145 | Jena Bioscience GmbH | 4Kits | EUR 689.8 |
JBScreen PEG/Salt 1 - 4 |
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M-CS-145 | MiTeGen | 4 Kits | EUR 858 |
Description: JBScreen PEG/Salt 1 - 4 |
JBScreen Nuc-Pro 1 - 4 |
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CS-185 | Jena Bioscience GmbH | 4Kits | EUR 1085 |
JBScreen Nuc-Pro 1 - 4 |
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M-CS-185 | MiTeGen | 4 Kits | EUR 1349 |
Description: JBScreen Nuc-Pro 1 - 4 |
JBScreen Pentaerythritol 1 - 4 |
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CS-195 | Jena Bioscience GmbH | 4Kits | EUR 1084.5 |
JBScreen Pentaerythritol 1-4 |
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M-CS-195 | MiTeGen | 4 Kits | EUR 1349 |
Description: JBScreen Pentaerythritol 1-4 |
JBScreen Membrane 4 (MPD, & Salt based) |
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M-CS-304L | MiTeGen | 24 solutions | EUR 414 |
Description: JBScreen Membrane 4 (MPD, & Salt based) |
JBScreen Membrane 1-4 - All 4 kits |
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M-CS-309 | MiTeGen | 4 Kits | EUR 1349 |
Description: JBScreen Membrane 1-4 - All 4 kits |
JBScreen Pentaerythritol 1 (PEP 426 based) |
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M-CS-191 | MiTeGen | 24 solutions | EUR 414 |
Description: JBScreen Pentaerythritol 1 (PEP 426 based) |
JBScreen Pentaerythritol 2 (PEP 629 based) |
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M-CS-192 | MiTeGen | 24 solutions | EUR 414 |
Description: JBScreen Pentaerythritol 2 (PEP 629 based) |
JBScreen Pentaerythritol 3 (PEE 270 based) |
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M-CS-193 | MiTeGen | 24 solutions | EUR 414 |
Description: JBScreen Pentaerythritol 3 (PEE 270 based) |
There is no limit to the number of genes that can be used to search the database in one query. secondary analysis such as gene ontology, regulatory factors, the location of the plot chromosome or tissue expression of IFN-regulated genes (IRGs) can be done in Interferome v2.0, or data can be downloaded in text format that is readily compatible with the common secondary analysis program. Given the importance of IFN to the innate immune response in infectious, inflammatory diseases and cancer, this upgrade of Interferome to version 2.0 will facilitate the identification of signatures of genes important in the pathogenesis of this disease.
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