BACKGROUND
public sharing of scientific data have been assumed to be more important in the era of omics. Transparency is needed for confirmation and validation, and some help inspectors in extracting the maximum value from large data sets. Thus, the filing of the database and the provision of the Minimum Information About Microarray Experiment (MIAME) (3) required by most journals as a prerequisite for review or acceptance.

METHOD
In this study, the rate of submission of the data and compliance MIAME reviewed for 127 articles were included based microarray microRNA (miRNA) profiling and published from July 2011 until April 2012 in the journal that published the largest number of such articles – PLoS ONE, the Journal of Biological Chemistry, Blood and Oncogenes – along with articles from other journals 9, including Clinical Chemistry, that the smaller number of articles published array-based.

RESULTS
Overall, the submission of data reported in the publication for <40% of all articles, and nearly 75% of the articles were MIAME obedient. On average, the article which includes full data submission scored significantly higher on a quality metric of articles with limited or no data submission, and studies with an adequate description of the proportional method including a larger number of repeat experiments. Finally, some articles are not MIAME compliant, data reanalysis reveals less than full support for the conclusions published, in one case leading to the retraction.

CONCLUSION
These findings angle hypothesis that the reluctance to share data related to the low quality studies and investigations showed that the majority of miRNA arrays underpowered and / or potentially compromised by the lack of appropriate reporting and data submission.

DeltaNp63 different isoforms regulate gene expression in squamous cell carcinoma: identification of Cox-2 as a new p63 targets.

P53 homologue of p63 produced six different isoforms that are important in the development of epithelial tissues and squamous cell carcinoma of the head and neck (SCCHN). In SCCHN, p63 isoform expression is very complex, with over-expression and isoform DeltaNp63 p63beta in many tumors. Until recently, little was known about the function of the different isoforms and elucidating DeltaNp63 distinctive properties of isoform DeltaNp63 will help to explain how they affect tumor biology.

With the gene expression profile SCCHN cells over-expressing isoform DeltaNp63 we identify the different effects of the three isoforms, with DeltaNp63beta become more effective in gene induction of DeltaNp63alpha and DeltaNp63gamma, while the most effective DeltaNp63gamma suppress gene expression. Thus, tumors express low levels even DeltaNp63beta or DeltaNp63gamma may have distinct clinicopathological characteristics essential for metastasis and response to therapy. Induction of cyclooxygenase-2 (Cox-2) shown by each isoform and data independently confirmed by quantitative RT-PCR and western blotting.

Nitric Oxide Cell-Based HTS Assay Kit
K979-100	Biovision		EUR 653

TW,HTS,6.5MM,0.4UM,S,IND,1/2
3396	CORNING	1/pk	EUR 399
Description: Permeable Support; HTS Transwell

TW,HTS,6.5MM,0.4UM,S,BK,12/12
3397	CORNING	12/pk	EUR 1955
Description: Permeable Support; HTS Transwell

TW,HTS,6.5MM,3.0UM,S,IND,1/2
3398	CORNING	1/pk	EUR 399
Description: Permeable Support; HTS Transwell

TW,HTS,6.55MM,3.0UM,S,BK,12/12
3399	CORNING	12/pk	EUR 1955
Description: Permeable Support; HTS Transwell

Caspase-3 DEVD-R110 Fluorometric HTS Assay Kit
30009-1	Biotium	1KIT	EUR 100
Description: Minimum order quantity: 1 unit of 1KIT

Caspase-3 DEVD-R110 Fluorometric HTS Assay Kit
30009-2	Biotium	1KIT	EUR 226
Description: Minimum order quantity: 1 unit of 1KIT

Caspase-3 DEVD-R110 Fluorometric HTS Assay Kit
30009-3	Biotium	1KIT	EUR 809
Description: Minimum order quantity: 1 unit of 1KIT

Caspase-8 IETD-R110 Fluorometric HTS Assay Kit
30012-1	Biotium	1KIT	EUR 100
Description: Minimum order quantity: 1 unit of 1KIT

Caspase-8 IETD-R110 Fluorometric HTS Assay Kit
30012-2	Biotium	1KIT	EUR 358
Description: Minimum order quantity: 1 unit of 1KIT

Caspase-8 IETD-R110 Fluorometric HTS Assay Kit
30012-3	Biotium	1KIT	EUR 1627
Description: Minimum order quantity: 1 unit of 1KIT

Steady-Luc Firefly HTS Assay Kit (12 ml)
30028-1	Biotium	1KIT	EUR 139
Description: Minimum order quantity: 1 unit of 1KIT

Steady-Luc Firefly HTS Assay Kit (100 ml)
30028-2	Biotium	1KIT	EUR 610
Description: Minimum order quantity: 1 unit of 1KIT

Steady-Luc Firefly HTS Assay Kit (10x100 ml)
30028-3	Biotium	1KIT	EUR 3145
Description: Minimum order quantity: 1 unit of 1KIT

3D Culture HTS Cell Viability Assay Kit (Colorimetric)
K2032-100	Biovision	100 assays	EUR 379

TW,HTS,CULTURE RESERVOIR,NT,S,BK,12PL/48
3395	CORNING	12/pk	EUR 295
Description: Permeable Support; HTS Transwell

3D Cell Culture HTS Cell Viability Complete Assay Kit
K948-100	Biovision		EUR 343

TRANSWELL,96WL,HTS,W/3.0 MEMBRANE,S,IND,1/2
3385	CORNING	1/pk	EUR 179
Description: Permeable Support; HTS Transwell

TRANSWELL,96WL,HTS,W/3.0 MEMBRANE,S,BK,4/8
3386	CORNING	4/pk	EUR 626
Description: Permeable Support; HTS Transwell

TRANSWELL,96WL, HTS,W/5.0UM MEMBRANE,S,BK,4/8
3387	CORNING	4/pk	EUR 626
Description: Permeable Support; HTS Transwell

TRANSWELL,96WL,HTS,W/5.0 MEMBRANE,S,BK,1/2
3388	CORNING	1/pk	EUR 179
Description: Permeable Support; HTS Transwell

TRANSWELL,96WL,WHITE,HTS RECEIVER,TCT,S,BK,10/10
3783	CORNING	10/pk	EUR 158
Description: Permeable Support; HTS Transwell

HTS TRANSWELL,TISSUE CULTURE TREATED RESERVOIR,S,BK,12/48
4395	CORNING	12/pk	EUR 321
Description: Permeable Support; HTS Transwell

Steady-Luc Firefly HTS Assay Kit (trial size)(4 mL)
30028-T	Biotium	1KIT	EUR 94
Description: Minimum order quantity: 1 unit of 1KIT

Human Breast Slide (Normal) (5 slides/pk)
HTS-10001	Alpha Diagnostics	1 pk	EUR 286

Human Breast Slide (Benign) (5 slides/pk)
HTS-10003	Alpha Diagnostics	1 pk	EUR 286

Human Breast Slide (Fibroadenoma) (5 slides/pk)
HTS-10004	Alpha Diagnostics	1 pk	EUR 286

Human Breast Slide (Carcinoma) (5 slides/pk)
HTS-10009	Alpha Diagnostics	1 pk	EUR 286

Human Breast Slide (Ductal Carcinoma In Situ (DCIS)) (5 slides/pk)
HTS-10010	Alpha Diagnostics	1 pk	EUR 286

Human Breast Slide (Well differentiated Carcinoma) (5 slides/pk)
HTS-10012	Alpha Diagnostics	1 pk	EUR 286

Human Breast Slide (Poorly differentiated carcinoma) (5 slides/pk)
HTS-10013	Alpha Diagnostics	1 pk	EUR 286

Human Breast Slide (Abnormal) (5 slides/pk)
HTS-10020	Alpha Diagnostics	1 pk	EUR 286

Human Lung Slide (Normal) (5 slides/pk)
HTS-10101	Alpha Diagnostics	1 pk	EUR 286

Human Lung Slide (Tumor) (5 slides/pk)
HTS-10102	Alpha Diagnostics	1 pk	EUR 286

Human Lung Slide (Small cell carcinoma) (5 slides/pk)
HTS-10103	Alpha Diagnostics	1 pk	EUR 286

Human Lung Slide (Non-small cell carcinoma) (5 slides/pk)
HTS-10104	Alpha Diagnostics	1 pk	EUR 286

Human Lung Slide (Squamous cell carcinoma) (5 slides/pk)
HTS-10105	Alpha Diagnostics	1 pk	EUR 286

Human Lung Slide (Adenocarcinoma) (5 slides/pk)
HTS-10106	Alpha Diagnostics	1 pk	EUR 286

Human Lung Slide (Abnormal) (5 slides/pk)
HTS-10110	Alpha Diagnostics	1 pk	EUR 286

Human Liver Slide (Normal) (5 slides/pk)
HTS-10201	Alpha Diagnostics	1 pk	EUR 286

Human Liver Slide (Malignant Tumor) (5 slides/pk)
HTS-10220	Alpha Diagnostics	1 pk	EUR 286

Human Liver Slide (Hepatocellular Carcinoma) (5 slides/pk)
HTS-10222	Alpha Diagnostics	1 pk	EUR 286

Human Liver Slide (Abnormal) (5 slides/pk)
HTS-10237	Alpha Diagnostics	1 pk	EUR 286

Human Liver Slide (Necrotic tissue) (5 slides/pk)
HTS-10246	Alpha Diagnostics	1 pk	EUR 286

Human Brain Slide (Normal) (5 slides/pk)
HTS-10301	Alpha Diagnostics	1 pk	EUR 286

Human Brain Slide (Tumor) (5 slides/pk)
HTS-10302	Alpha Diagnostics	1 pk	EUR 286

Human Kidney Slide (Normal) (5 slides/pk)
HTS-10401	Alpha Diagnostics	1 pk	EUR 286

Human Kidney Slide (Tumor) (5 slides/pk)
HTS-10402	Alpha Diagnostics	1 pk	EUR 286

Human Kidney Slide (Renal Cell Neoplasia) (5 slides/pk)
HTS-10403	Alpha Diagnostics	1 pk	EUR 286

Human Kidney Slide (Clear Cell Renal Cell Carcinoma) (5 slides/pk)
HTS-10405	Alpha Diagnostics	1 pk	EUR 286

Human Kidney Slide (Papillary Renal Cell Carcinoma) (5 slides/pk)
HTS-10407	Alpha Diagnostics	1 pk	EUR 286

Human Kidney Slide (Renal Cell Carcinoma) (5 slides/pk)
HTS-10414	Alpha Diagnostics	1 pk	EUR 286

Human Kidney Slide (Abnormal) (5 slides/pk)
HTS-10455	Alpha Diagnostics	1 pk	EUR 286

Human Heart Slide (Normal) (5 slides/pk)
HTS-10501	Alpha Diagnostics	1 pk	EUR 286

Human Heart Slide (Tumor) (5 slides/pk)
HTS-10502	Alpha Diagnostics	1 pk	EUR 286

Human Heart Slide (Myxoma) (5 slides/pk)
HTS-10503	Alpha Diagnostics	1 pk	EUR 286

Human Heart Slide (Abnormal) (5 slides/pk)
HTS-10525	Alpha Diagnostics	1 pk	EUR 286

Human Prostate Tissue Slide (Hyperplasia) (5 slides/pk)
HTS-10635	Alpha Diagnostics	1 pk	EUR 286

Human Colorectal Slide (Normal) (5 slides/pk)
HTS-10701	Alpha Diagnostics	1 pk	EUR 286

Human Colorectal Slide (Benign) (5 slides/pk)
HTS-10702	Alpha Diagnostics	1 pk	EUR 286

Human Colorectal Slide (Adenocarcinoma) (5 slides/pk)
HTS-10704	Alpha Diagnostics	1 pk	EUR 286

Human Colorectal Colon Slide (Mucinous Carcinoma) (5 slides/pk)
HTS-10705	Alpha Diagnostics	1 pk	EUR 286

Human Colorectal Colon Slide (Unclassified Carcinoma) (5 slides/pk)
HTS-10710	Alpha Diagnostics	1 pk	EUR 286

Human Colorectal Colon Slide (Abnormal) (5 slides/pk)
HTS-10719	Alpha Diagnostics	1 pk	EUR 286

Human Stomach Tissue Slide (Normal) (5 slides/pk)
HTS-10801	Alpha Diagnostics	1 pk	EUR 286

Human Stomach Tissue Slide (Benign) (5 slides/pk)
HTS-10803	Alpha Diagnostics	1 pk	EUR 286

Human Stomach Tissue Slide (Carcinoma) (5 slides/pk)
HTS-10807	Alpha Diagnostics	1 pk	EUR 286

Human Stomach Tissue Slide (Adenocarcinoma) (5 slides/pk)
HTS-10809	Alpha Diagnostics	1 pk	EUR 286

Human Stomach Tissue Slide (Mucinous adenocarcinoma) (5 slides/pk)
HTS-10810	Alpha Diagnostics	1 pk	EUR 286

Human Stomach Tissue Slide (Signet Ring Cell Adenocarcinoma) (5 slides/pk)
HTS-10811	Alpha Diagnostics	1 pk	EUR 286

Human Stomach Tissue Slide (Carcinoma) (5 slides/pk)
HTS-10814	Alpha Diagnostics	1 pk	EUR 286

Human Stomach Tissue Slide (Abnormal) (5 slides/pk)
HTS-10826	Alpha Diagnostics	1 pk	EUR 286

Human Stomach Tissue Slide (Tumor) (5 slides/pk)
HTS-10827	Alpha Diagnostics	1 pk	EUR 286

Human Spleen Tissue Slide (Unknown) (5 slides/pk)
HTS-10900	Alpha Diagnostics	1 pk	EUR 286

Human Spleen Tissue Slide (Normal) (5 slides/pk)
HTS-10901	Alpha Diagnostics	1 pk	EUR 286

Human Spleen Tissue Slide (Benign) (5 slides/pk)
HTS-10903	Alpha Diagnostics	1 pk	EUR 286

Human Thyroid Tissue Slide (Benign) (5 slides/pk)
HTS-11002	Alpha Diagnostics	1 pk	EUR 286

Human Thyroid Tissue Slide (Follicular Carcinoma) (5 slides/pk)
HTS-11006	Alpha Diagnostics	1 pk	EUR 286

Human Thyroid Tissue Slide (Papillary Carcinoma) (5 slides/pk)
HTS-11007	Alpha Diagnostics	1 pk	EUR 286

Human Thyroid Tissue Slide (Abnormal) (5 slides/pk)
HTS-11018	Alpha Diagnostics	1 pk	EUR 286

Human Pancreas Tissue Slide (normal) (5 slides/pk)
HTS-11101	Alpha Diagnostics	1 pk	EUR 286

Human Pancreas Tissue Slide (Adenocarcinoma) (5 slides/pk)
HTS-11105	Alpha Diagnostics	1 pk	EUR 286

Human Pancreas Tissue Slide (Abnormal) (5 slides/pk)
HTS-11106	Alpha Diagnostics	1 pk	EUR 286

Human Ovary Tissue Slide (Normal) (5 slides/pk)
HTS-11201	Alpha Diagnostics	1 pk	EUR 286

Human Ovary Tissue Slide (Benign) (5 slides/pk)
HTS-11202	Alpha Diagnostics	1 pk	EUR 286

Human Ovary Tissue Slide (Benign Epithelial Tumor) (5 slides/pk)
HTS-11203	Alpha Diagnostics	1 pk	EUR 286

Human Ovary Tissue Slide (Benign Sex Chord Stromal tumor) (5 slides/pk)
HTS-11204	Alpha Diagnostics	1 pk	EUR 286

Human Ovary Tissue Slide (Malignant tumor) (5 slides/pk)
HTS-11206	Alpha Diagnostics	1 pk	EUR 286

Human Ovary Tissue Slide (Epithelial tumor) (5 slides/pk)
HTS-11207	Alpha Diagnostics	1 pk	EUR 286

Human Ovary Tissue Slide (Abnormal) (5 slides/pk)
HTS-11210	Alpha Diagnostics	1 pk	EUR 286

Human Cervix Slide (Normal) (5 slides/pk)
HTS-11301	Alpha Diagnostics	1 pk	EUR 286

Human Cervix Slide (Benign) (5 slides/pk)
HTS-11303	Alpha Diagnostics	1 pk	EUR 286

Human Cervix Slide (Condyloma acuminatum) (5 slides/pk)
HTS-11304	Alpha Diagnostics	1 pk	EUR 286

Human Cervix Slide (Interepithelial Neoplasia (squamous dysplasia)) (5 slides/pk)
HTS-11305	Alpha Diagnostics	1 pk	EUR 286

Human Cervix Slide (Squamous Cell Carcinoma) (5 slides/pk)
HTS-11307	Alpha Diagnostics	1 pk	EUR 286

Human Cervix Slide (Abnormal) (5 slides/pk)
HTS-11316	Alpha Diagnostics	1 pk	EUR 286

Human Uterus Tissue Slide (Normal) (5 slides/pk)
HTS-11401	Alpha Diagnostics	1 pk	EUR 286

Human Uterus Tissue Slide (Benign) (5 slides/pk)
HTS-11402	Alpha Diagnostics	1 pk	EUR 286

Human Uterus Tissue Slide (Adenocarcinoma) (5 slides/pk)
HTS-11404	Alpha Diagnostics	1 pk	EUR 286

Human Uterus Tissue Slide (Endometrioid Adenocarcinoma) (5 slides/pk)
HTS-11405	Alpha Diagnostics	1 pk	EUR 286

Human Uterus Tissue Slide (Papillary serous Adenocarcinoma) (5 slides/pk)
HTS-11407	Alpha Diagnostics	1 pk	EUR 286

Human Uterus Tissue Slide (Spindle cell tumor) (5 slides/pk)
HTS-11418	Alpha Diagnostics	1 pk	EUR 286

Human Uterus Tissue Slide (Abnormal) (5 slides/pk)
HTS-11419	Alpha Diagnostics	1 pk	EUR 286

Human Uterus Tissue Slide (Adenomyoma) (5 slides/pk)
HTS-11432	Alpha Diagnostics	1 pk	EUR 286

Human Lymphoid Tissue Slide (Abnormal) (5 slides/pk)
HTS-11504	Alpha Diagnostics	1 pk	EUR 286

Human Lymphoid Tissue Slide (Appendix Abnormal) (5 slides/pk)
HTS-11515	Alpha Diagnostics	1 pk	EUR 286

Human Lymphoid Tissue Slide (Lymph node normal) (5 slides/pk)
HTS-11521	Alpha Diagnostics	1 pk	EUR 286

Human Lymphoid Tissue Slide (Lymph node benign) (5 slides/pk)
HTS-11523	Alpha Diagnostics	1 pk	EUR 286

Human Lymphoid Tissue Slide (Lymph node malignant) (5 slides/pk)
HTS-11524	Alpha Diagnostics	1 pk	EUR 286

Human Lymphoid Tissue Slide (Lymph node abnormal) (5 slides/pk)
HTS-11525	Alpha Diagnostics	1 pk	EUR 286

Human Lymphoid Tissue Slide (Tonsil benign) (5 slides/pk)
HTS-11533	Alpha Diagnostics	1 pk	EUR 286

Human Leukemias/Lymphomas Tissue Slide (Leukemia Spleen) (5 slides/pk)
HTS-11601	Alpha Diagnostics	1 pk	EUR 286

Human Leukemias/Lymphomas Tissue Slide (Lymphoma) (5 slides/pk)
HTS-11603	Alpha Diagnostics	1 pk	EUR 286

Human Leukemias/Lymphomas Tissue Slide (Mixed Leukemia and Lymphoma) (5 slides/pk)
HTS-11606	Alpha Diagnostics	1 pk	EUR 286

Human Testis Tissue Slide (Normal) (5 slides/pk)
HTS-11701	Alpha Diagnostics	1 pk	EUR 286

Human Testis Tissue Slide (Abnormal) (5 slides/pk)
HTS-11710	Alpha Diagnostics	1 pk	EUR 286

Human Small Intestine Tissue Slide (Squamous Cell Carcinoma) (5 slides/pk)
HTS-11801	Alpha Diagnostics	1 pk	EUR 286

Human Small Intestine Tissue Slide (Squamous Cell Carcinoma) (5 slides/pk)
HTS-11814	Alpha Diagnostics	1 pk	EUR 286

Human Small Intestine Tissue Slide (Squamous Cell Carcinoma) (5 slides/pk)
HTS-11815	Alpha Diagnostics	1 pk	EUR 286

Human Small Intestine Tissue Slide (Squamous Cell Carcinoma) (5 slides/pk)
HTS-11824	Alpha Diagnostics	1 pk	EUR 286

Human Urogenital Tissue Slide (Fallopian Tube normal) (5 slides/pk)
HTS-11901	Alpha Diagnostics	1 pk	EUR 286

Human Urogenital Tissue Slide (Fallopian Tube Benign) (5 slides/pk)
HTS-11903	Alpha Diagnostics	1 pk	EUR 286

Human Urogenital Tissue Slide (Fallopian Tube Abnormal) (5 slides/pk)
HTS-11905	Alpha Diagnostics	1 pk	EUR 286

Human Urogenital Tissue Slide (Placenta Benign) (5 slides/pk)
HTS-11913	Alpha Diagnostics	1 pk	EUR 286

Human Urogenital Tissue Slide (Vas Deferens Normal) (5 slides/pk)
HTS-11961	Alpha Diagnostics	1 pk	EUR 286

Human Urogenital Tissue Slide (Vas Deferens Benign) (5 slides/pk)
HTS-11963	Alpha Diagnostics	1 pk	EUR 286

Human Salivary Gland Tissue Slide (Mucoepidermoid carcinoma) (5 slides/pk)
HTS-12109	Alpha Diagnostics	1 pk	EUR 286

Human Salivary Gland Tissue Slide (Abnormal) (5 slides/pk)
HTS-12128	Alpha Diagnostics	1 pk	EUR 286

Human Penis Tissue Slide (Malignant) (5 slides/pk)
HTS-12204	Alpha Diagnostics	1 pk	EUR 286

Human Soft Tissue Slide (Benign) (5 slides/pk)
HTS-12303	Alpha Diagnostics	1 pk	EUR 286

Human Soft Tissue Slide (Abnormal) (5 slides/pk)
HTS-12305	Alpha Diagnostics	1 pk	EUR 286

Human Soft Tissue Slide (Adipose Undiagnosed) (5 slides/pk)
HTS-12310	Alpha Diagnostics	1 pk	EUR 286

Human Soft Tissue Slide (Adipose Normal) (5 slides/pk)
HTS-12311	Alpha Diagnostics	1 pk	EUR 286

Human Soft Tissue Slide (Adipose Benign) (5 slides/pk)
HTS-12313	Alpha Diagnostics	1 pk	EUR 286

Human Soft Tissue Slide (Adipose Lipoma) (5 slides/pk)
HTS-12314	Alpha Diagnostics	1 pk	EUR 286

Human Soft Tissue Slide (Adipose Liposarcoma) (5 slides/pk)
HTS-12316	Alpha Diagnostics	1 pk	EUR 286

Human Soft Tissue Slide (Adipose Abnormal) (5 slides/pk)
HTS-12317	Alpha Diagnostics	1 pk	EUR 286

Human Soft Tissue Slide (Skeletal Muscle Normal) (5 slides/pk)
HTS-12341	Alpha Diagnostics	1 pk	EUR 286

Human Soft Tissue Slide (Skeletal Muscle Benign) (5 slides/pk)
HTS-12343	Alpha Diagnostics	1 pk	EUR 286

Human Soft Tissue Slide (Skeletal Muscle Malignant) (5 slides/pk)
HTS-12345	Alpha Diagnostics	1 pk	EUR 286

Human Gall Bladder Slide (Normal) (5 slides/pk)
HTS-12401	Alpha Diagnostics	1 pk	EUR 286

Human Gall Bladder Slide (Benign) (5 slides/pk)
HTS-12403	Alpha Diagnostics	1 pk	EUR 286

Human Gall Bladder Slide (Abnormal) (5 slides/pk)
HTS-12417	Alpha Diagnostics	1 pk	EUR 286

Human Esophogus Slide (Squamous Cell Carcinoma) (5 slides/pk)
HTS-12505	Alpha Diagnostics	1 pk	EUR 286

Human Bladder Slide (Normal) (5 slides/pk)
HTS-12601	Alpha Diagnostics	1 pk	EUR 286

Human Bladder Slide (Malignant epithelial tumor) (5 slides/pk)
HTS-12610	Alpha Diagnostics	1 pk	EUR 286

Human Bladder Slide (Papillary Carcinoma) (5 slides/pk)
HTS-12612	Alpha Diagnostics	1 pk	EUR 286

Human Skin Tissue Slide (Normal) (5 slides/pk)
HTS-12701	Alpha Diagnostics	1 pk	EUR 286

Human Skin Tissue Slide (Benign) (5 slides/pk)
HTS-12702	Alpha Diagnostics	1 pk	EUR 286

Human Skin Tissue Slide (Squamous Cell Carcinoma) (5 slides/pk)
HTS-12704	Alpha Diagnostics	1 pk	EUR 286

Human Skin Tissue Slide (Basal Cell Carcinoma) (5 slides/pk)
HTS-12705	Alpha Diagnostics	1 pk	EUR 286

Human Skin Tissue Slide (Abnormal) (5 slides/pk)
HTS-12706	Alpha Diagnostics	1 pk	EUR 286

No direct binding of DeltaNp63 to Cox-2 promoter could be seen, can not be evidence for Cox-2 induction as a consequence of activated NF-kappaB pathway responses found. Known as Cox-2 inhibiting response to radiotherapy in patients with SCCHN, the data shows an additional mechanism through which DeltaNp63 act to promote cell survival and affect the therapeutic response SCCHN. MIAME-compliant data has been stored in the database MIAME Express